Oral Abstracts
ID:3006 RNA Therapeutics and Anabolic Gene Delivery for Tissue Regeneration
- Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan
Correspondence to:
Yu-Chen Hu,
Department of Chemical Engineering, National Tsing Hua University, Hsinchu, Taiwan.
Email:
[email protected].
Volume & Issue:
Vol. 4 No. S (2017): Abstract Proceeding: International conference INNOVATIONS IN CANCER RESEARCH AND REGENERATIVE MEDICINE 2017
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Page No.:
S18
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DOI:
10.15419/bmrat.v4iS.224
Published:
2017-09-05
Abstract
Regenerative medicine requires coordinated functions of cells, materials and appropriate signaling. Recent years have witnessed the marriage of regenerative medicine and gene delivery by which various genes encoding anabolic/catabolic proteins or RNA therapeutics are delivered into cells to potentiate the tissue regeneration. This presentation will focus on the use of viral vectors for genetic modification of mesenchymal stem cells derived from bone marrow or adipose tissue for tissue regeneration. In particular, emphasis is placed on the applications of baculovirus, an emerging nonpathogenic gene delivery vector, for the delivery of various anabolic genes and miRNA mimics/sponges to repair tissues