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ID: 1033 Case report: Results of the first case of Stem cell transplantation from cord blood cryopreservation for β-thalassemia patient at Vinmec International Hospital

Phu NT 1, *
Phuong T.M. Dam 1
Dung NT 2
Lan PT 2
Liem NT 1
  1. Vinmec Research Institute of Stem cell and gene technology
  2. Hematology – Pediatrics – Oncology Department, Vinmec International Hospital
Correspondence to: Phu NT, Vinmec Research Institute of Stem cell and gene technology. Email: [email protected].

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Copyright The Author(s) 2024. This article is published with open access by BioMedPress. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. 

Abstract

Background: To report the result of first case of β thalassemia, which is successfully transplanted by using allogeneic cord blood at the Vinmec International Hospital.

 Methods: Male patient, born in January 2014, was diagnosed with β thalassemia at 3 months of age. Patient was received cord blood transplantation from his younger sibling who matches HLA index of 10/10 in August 2016.

 Results: The number of cells in cord blood met high quality and after 30 days of transplantation, engraftment of patient fully developed with the Chimerism test was 100%. After 3 months of follow-up, it was demonstrated that the transplantation was successful.

 Conclusion: We present an effective case of hematopoietic stem cell transplantation from human umbilical cord blood of sibling for treatment of thalassemia.

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