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ID: 1038 Hydrothermal synthesis of carbon nanodots from millets for cancer cells imaging

Quang Ngo Khoa 1
Tran Thi Xuan Thuy 1
Che Thi Cam Ha 1, *
  1. Hue College of Sciences, Hue City, Vietnam
Correspondence to: Che Thi Cam Ha, Hue College of Sciences, Hue City, Vietnam. Email: [email protected].

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Copyright The Author(s) 2024. This article is published with open access by BioMedPress. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. 

Abstract

We presented a green, simple and economical method to synthesize carbon nanodots (C-dots) from millets using hydrothermal synthesis route. The obtained C-dots have average diameter ranging from 6 to 8 nm. Optical measurements showed the formation of hydroxyl, carbonyl/carboxyl, amino functional groups on the particle surfaces, resulting in their high hydrophilicity and bioconjugation. After treatment with C-dots, human cervical and lung cancer cells became bright and exhibited multicolor fluorescence under different excitation wavelength. The achievement demonstrated potential applications of fluorescent C-dots in the field of biomedical application, especially in diagnostic disease techniques.

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