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ID: 1042 Production of PHA from Pseudomonas Plecoglossicida and its biomedical application

Sabarinathan Devaraj 1, *
  1. Ph.D Scholar Department of Microbial Biotechnology, Bharathiar University Coimbatore, Tamilnadu 641046, India
Correspondence to: Sabarinathan Devaraj, Ph.D Scholar Department of Microbial Biotechnology, Bharathiar University Coimbatore, Tamilnadu 641046, India. Email: [email protected].

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Copyright The Author(s) 2024. This article is published with open access by BioMedPress. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. 

Abstract

To reduce the amount of plastic waste, world-wide programs for efficient management of utilized plastic materials, such as recycling, have been started PHAs could be completely relied on replacing the conventional plastics as they share similar thermo mechanical properties with the petrochemical based plastics. PHA exhibit high level of biocompatibility and biodegradability, hence they are used for several biomedical applications. PHA extracted from Pseudomonas plecoglossicida checked for its ability to attach cancer cells was investigated. Cancer cells showed high affinity of adherence on the PHA sheets used. Contact angle detection have proved that only cancer cells showed the adherence effect and normal cells did not exhibit such adherence property towards the PHA sheets which was further authenticated by contact angle observations. Hence, PHA sheets can be effectively used as a valid target for the contact angle detection of cancer cells.

 

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