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Application of electrochemical aptasensors in detection of cancer biomarkers

Masoud Negahdary 1, *
Ali Moradi 2
Hossein Heli 1
  1. Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
  2. Department of Biochemistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
Correspondence to: Masoud Negahdary, Nanomedicine and Nanobiology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran. Email: [email protected].
Volume & Issue: Vol. 6 No. 7 (2019) | Page No.: 3315-3324 | DOI: 10.15419/bmrat.v6i7.558
Published: 2019-07-28

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This article is published with open access by BioMedPress. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. 

Abstract

Today, the late diagnosis of cancers is a big challenge, and using novel diagnostic techniques will provide essential, faster and more accurate treatments. Unfortunately, existing common and traditional diagnostic methods have not been helpful completely and most cancers are diagnosed too late. Recently, researchers have found new diagnostic methods against cancers by aptasensors; these sensory systems can detect involved biomarkers in various cancers so that the research in this field is continued strictly. Aptasensors can detect cancer markers in small quantities and high selectivity; moreover, other advantages of cancer aptasensors such as optimized time and cost saving can be considered. In addition, the aptasensors have been used in the diagnosis of the effective and related factors in cancer therapy follow-up. Here, the most researches about cancer aptasensors and other involved markers were collected, reviewed and described.

 

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