Convalescent plasma successfully treats a severe COVID-19 patient with multi-organ failure
- Department of Anesthesiology, Kermanshah University of Medical Sciences. Kermanshah, Iran
- Department of Biotechnology, Kermanshah Blood Transfusion Organization. Kermanshah, Iran
- Department of Hematology, Regenerative Medicine Research Center, Kermanshah University of Medical Sciences. Kermanshah, Iran
- Department of Pulmonary, Kermanshah University of Medical Sciences. Kermanshah, Iran
- Department of Infectious Diseases and Tropical Medicine, Kermanshah University of Medical Sciences. Kermanshah, Iran
- Department of Laboratory Sciences, Kermanshah University of Medical Sciences. Kermanshah, Iran
- Department of General Surgery, Kermanshah University of Medical Sciences. Kermanshah, Iran
- Department of Hematology and Medical Oncology, Regenerative Medicine Research Center, Kermanshah University of Medical Sciences. Kermanshah, Iran
Abstract
Due to the high mortality rate of coronavirus disease 2019 (COVID-19) and the lack of specific treatment for the disease, it is essential to find new therapies. The present case report aimed to assess the efficiency of convalescent plasma in patients with severe acute respiratory syndrome coronavirus 2. We reported a severe case of COVID-19 with multi-organ failure, who had reduced oxygen saturation after several courses of antiviral therapy. Moreover, computed tomography (CT) scan results showed patchy lesions in the base of lungs. Therapeutic measures, including endotracheal intubation and plasmapheresis with convalescent plasma, were performed for the patient; subsequently, good responses to the treatments were observed. Our findings demonstrate that convalescent plasma improves pulmonary lesions and the patient's clinical status.